A biopharmaceutical is a medicine whose active substance is made by a living organism. The most popular subset of biological drugs are recombinant therapeutic proteins that are biotechnologically manufactured in living sources including human, animal, plant, fungal or microbial cells. The majority of these products is produced in microbial cells, namely bacteria.


The production of therapeutic proteins in bacteria requires an efficient expression platform, consisting of an adapted bacterial strain and an optimized vector. This platform has to meet the scientific and technical demands of an industrial utilization, as well as fulfill the regulatory requirements of the pharmaceutical industry.


In this sponsored project, the goal is to establish a bacterial expression platform through an extensive scientific research work in collaboration with the Martin-Luther-University Halle-Wittenberg. Based on the results of this research, the development of a proprietary expression platform is planned, which is supposed to be used as a basis for the production of therapeutic proteins in Halle (Saale).


This project and the transfer of knowledge and research expertise into an industrial application is partly funded by the European Union, particularly the European Regional Development Fund (ERDF).

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